Oncolytics Biotech Inc. has announced that he has been awarded with the grant of U.S. Patent 7,300,650 entitled “Reovirus for the Treatment of Neoplasia.” The claims describe methods of using the reovirus to treat cancers that have inactivated PKR, whether the PKR is inactivated by mutation of Ras or by other factors. PKR is a host cellular protein responsible for preventing virus replication within a cell. Tumour cells lacking the activity of PKR are susceptible to reovirus replication and subsequently, cancer cell killing.
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